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Datasheet

Anti-PI3 Kinase p55 gamma Antibody

Goat Polyclonal

600-101-ML2S 600-101-ML2
25 µL 100 µg
WB, IHC, IF
Human, Mouse
Goat
$125.00 /Per Item
$475.00 /Per Item
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Background

PI 3-Kinases (phosphoinositide 3-kinases, PI 3-Ks) are a family of lipid kinases capable of phosphorylating the 3'OH of the inositol ring of phosphoinositides. They are responsible for coordinating a diverse range of cell functions including proliferation and survival. PIK3R3 (Phosphoinositide-3-Kinase Regulatory Subunit 3) binds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain and regulates their kinase activity. During insulin stimulation, it also binds to IRS-1. Anti-PIK3R3 Antibody is useful for researchers interested in cancer research, Asbestos-related lung carcinomas, intravenous Leiomyomatosis, ERK signaling, and mTOR Pathways.

Product Details

Anti-PI3 Kinase p55 gamma (PIK3R3) (GOAT) Antibody - 600-101-ML2
Goat Anti-PI3 Kinase p55 gamma Antibody, Goat Anti-PIK3R3 Antibody, Anti-p55 gamma Antibody, Phosphoinositide-3-Kinase Regulatory Subunit 3, Phosphatidylinositol 3-Kinase 55 KDa Regulatory Subunit Gamma, Phosphoinositide-3-Kinase, Regulatory Subunit 3 (Gamma), PtdIns-3-Kinase Regulatory Subunit P55-Gamma, PI3-Kinase Regulatory Subunit Gamma, PI3K Regulatory Subunit Gamma, PI3-Kinase Subunit P55-Gamma, P55PIK, Phosphatidylinositol 3-Kinase, Regulatory Subunit, Polypeptide 3 (P55, Gamma), Phosphatidylinositol 3-Kinase Regulatory Subunit Gamma, Phosphoinositide-3-Kinase Regulatory Subunit Gamma, PtdIns-3-Kinase Regulatory Subunit Gamma, P55-GAMMA, P55
Goat
Polyclonal
IgG

Target Details

PIK3R3  - View All PIK3R3 Products
Human, Mouse
Conjugated Peptide
Anti-PI3 Kinase p55 gamma antibody was prepared from whole goat serum produced by repeated immunizations with a synthetic peptide corresponding to a near N-Terminal portion of human PI3 Kinase p55 gamma conjugated to Keyhole Limpet Hemocyanin (KLH).
This affinity purified antibody is directed against human PI 3 Kinase p55 gamma.  This product was affinity purified from monospecific antiserum by immunoaffinity purification.   A BLAST analysis was used to suggest cross-reactivity with the antigen based on 100% homology with the immunizing sequence to mouse and rat, 94.1% homology to bovine.

Application Details

IF, IHC, WB
Anti-PI3 Kinase p55 gamma Antibody has been tested in WB, IF, and IHC.  Expect bands ~44, 47, 54kDa in western blot using appropriate tissues or lysates.  Positive control used: mouse testis in WB; A431 cells in IF; Human testis and Human tonsil tissue in IHC.

Formulation

Liquid (sterile filtered)
1.02 mg/ml by UV absorbance at 280 nm
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
0.01% (w/v) Sodium Azide
None

Shipping & Handling

Dry Ice
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
Expiration date is one (1) year from date of receipt.

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This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.