Leica has collaborated with Rockland Immunochemicals to jointly analyze the sub-cellular localization of Akt using high-resolution STED microscopy.

Leica STED super-resolution microscopy allows for the investigation of cellular structural details beyond the resolution of conventional confocal microscopy. This has allowed an unparalleled ability to visualize cellular events. Indeed, STED imaging allowed for the first time to clearly associate the activated Akt with tubulin network early after EGF stimulation. Tubulin—a protein used by cells to form microtubules—interacting with Akt could facilitate its migration upon activation. As it is known that AKT plays an essential role in cancer cell signaling, this unprecedented direct observation could initiate and open an exciting new avenue in cancer research.
 
 

Leica
1700 Leider Lane
Buffalo Grove, IL 60089
Phone: +1 800-248-0123
Fax: +1 847-236-3009

Rockland Immunochemicals Inc.
Gilbertsville, PA 19525
E-mail: orders@rockland-inc.com
Phone: 800.656.7625
Fax: 610.367.7825

 
 
 
This message has been sent and is copyright protected by Rockland Inc. 2013. All rights reserved.