Research published in Mol. Cell. Biol (Ashburner et al., 2001)
using Rockland NF-kB p65 specific antibodies
, demonstrates that the transactivation function of NF-kB is regulated through interaction with histone deacetylase (HDAC)
corepressor proteins. The transactivation function of NF-kB is regulated through association of the p65 (RelA)
subunit with HDAC corepressor proteins.
American Society for Microbiology:
The p65 (RelA) Subunit of NF-kB Interacts with the Histone Deacetylase (HDAC) Corepressors HDAC1 and HDAC2 To Negatively Regulate Gene Expression