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Catalog#: 100-401-405 Size/Unit: 200ul Price:  $245.00 Qty

Host: Rabbit Anti-NOTCH 1
Conjugation: Unconjugated
Background Information: Notch is synthesized in the endoplasmic reticulum as an inactive form which is proteolytically cleaved by a furin-like convertase (S1 cleavage) in the trans-golgi network before it reaches the plasma membrane to yield an active, ligand-accessible form.
Application Notes: Preliminary experiments show reactivity at a 1:1000 dilution by western blot. A strong response was detected by ELISA against the immunizing peptide.


General References:

1.  Bertrand FE, Eckfeldt CE, Lysholm AS, LeBien TW. (2000) Notch-1 and Notch-2 exhibit unique patterns of expression in human B-lineage cells. Leukemia. 12: 2095-102.   

2.  Gridley T. (2003) Notch signaling and inherited disease syndromes. Hum Mol Genet: 12: Suppl 1, R9-R13.   



 
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Catalog# Product Size/Unit Price Buy
100-401-407 Anti-NOTCH 1 (Cleaved N terminal) (Human specific) (Rabbit) 200ul $245.00
000-000-407 Anti-NOTCH 1 (Cleaved N terminal) (Human specific) CONTROL PEPTIDE For catalog # 100-401-407 50ug $75.00
000-000-405 Anti-NOTCH 1 (intra) (Human specific) CONTROL PEPTIDE For catalog # 100-401-405 50ug $75.00
000-000-409 Anti-NOTCH 1/2 (intra) (Human specific) CONTROL PEPTIDE For catalog # 100-401-409 50ug $55.00
100-401-408 Anti-NOTCH 2 (Cleaved N terminal) (Human specific) (Rabbit) 200ul $245.00
100-401-406 Anti-NOTCH 2 (intra) (Human specific) (Rabbit) 200ul $245.00
B501-0500 BLOTTO Immunoanalytical Grade (Non-Fat Dry Milk) 500 g $50.00
000-000-408 CONTROL PEPTIDE For catalog # 100-401-408 Anti-NOTCH 2 (Cleaved N terminal) (Human specific) 50ug $75.00
MB-201-0200 Protein Molecular Weight Marker (14 - 120kDa) 200ul $35.00
MB-201-2000 Protein Molecular Weight Marker (14 - 120kDa) 10x200ul $92.00
MB-201-1000 Protein Molecular Weight Marker (14 - 120kDa) 5 x 200 ul $55.00