Anti-ATM Protein Kinase pS1981 for WB, IF and IP (Mouse)

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Catalog#: 200-301-400

Size/Unit: 100ug

Price: $370.00

Qty

Host:	Mouse Anti-ATM Protein Kinase pS1981 for WB, IF & IP
Conjugation:	Unconjugated
Background Information:	ATM, the gene mutated in the hereditary disease ataxia-telangiectasia, codes for a protein kinase that acts as a master regulator of cellular responses to DNA double-strand breaks.
Application Notes:	Protein A Purified Mab Anti-ATM has been tested by ELISA and Western Blotting against both the native and recombinant forms of the protein. The antibody immunoprecipitates ATM from irradiated human and mouse cells.

Direct References:

1. Kitagawa R, Bakkenist CJ, McKinnon PJ, Kastan MB. (2004) Phosphorylation of SMC1 is a critical downstream event in the ATM-NBS1-BRCA1 pathway. Genes Dev. 18(12):1423-38.

2. Bakkenist CJ, Kastan MB. DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation. Nature. 2003 Jan 30;421(6922):499�506.

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Data Sheet

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610-1319	Peroxidase Conjugated Affinity Purified Anti-MOUSE IgG (H&L) (GOAT) (Min X Human Serum Proteins)	2mg	$105.00
610-4302	Peroxidase Conjugated Affinity Purified Anti-MOUSE IgG (H&L) (RABBIT)	2mg	$105.00
611-1322	Peroxidase Conjugated Affinity Purified Anti-RABBIT IgG (H&L) (GOAT) (Min X Human Serum Proteins)	2mg	$110.00
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MB-201-0200	Protein Molecular Weight Marker (14 - 120kDa)	200ul	$35.00
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