Extracellular Matrix (ECM) regulates a cell's dynamic behavior. Collagens are the most abundant glycoproteins in the ECM . Collagen can be divided into several families according to the types of structure they form: Fibrillar (Collagen I, Collagen II, Collagen III, Collagen V, Collagen XI; Facit (Collagen IX, Collagen XII, Collagen XIV); Short Chain (Collagen VIII, Collagen X); Basement membrane Collagen IV.