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Synaptotagmin 1 Antibody

Rabbit Polyclonal

612-401-E37
100 µL
WB
Mouse, Rat
Rabbit
$475.00 /Per Item
Availability: Ships in approximately 14 days
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Background

Synaptotagmin 1 Antibody detects Synaptotagmin 1, which is a synaptic vesicle membrane glycoprotein that is widely expressed throughout the CNS. It is generally thought to act as the Ca2+ sensor in the regulation of exocytosis and neurotransmitter release. Recent studies indicate that synaptotagmin’s Ca2+ mediated binding of SNAP25 is essential for the Ca2+ dependent triggering of membrane fusion. It has recently been demonstrated that discrete residues within the c(2)b binding domain of synaptotagmin 1 independently specify endocytic rate and synaptic vesicle size. Anti-Synaptotagmin 1 Antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.

Product Details

Anti-Synaptotagmin 1 (RABBIT) Antibody - 612-401-E37
Synaptotagmin-1, Synaptotagmin I, SytI, p65, Syt1
Rabbit
Polyclonal
IgG

Target Details

Sty1  - View All Sty1 Products
Mouse, Rat
Conjugated Peptide
Anti-Synaptotagmin 1 Antibody was produced in rabbit by repeated immunizations with synthetic peptide corresponding to amino acid residues specific to synaptotagmin 1.
Anti-Synaptotagmin 1 Antibody is directed against rat Synaptotagmin 1. Synaptotagmin I antibody was affinity purified from monospecific antiserum by immunoaffinity purification. Reactivity is expected from the following species based on 100% sequence homology: human, mouse, bovine, chicken and non-human primate tissues. Cross-reactivity with from other species has not been determined.

Application Details

WB
Anti-Synaptotagmin 1 antibody is tested for use in Western Blotting. Expect a band of approximately 65 kDa in size corresponding to synaptotagmin I protein in the appropriate cell lysate or extract. Researchers should determine optimal titers for applications that are not stated below.

Formulation

Liquid
0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
0.1 mg/ml Bovine Serum Albumin (BSA) - IgG and Protease free, 50% (v/v) Glycerol

Shipping & Handling

Dry Ice
Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
Expiration date is one (1) year from date of receipt.

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This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

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