![Histone H3 [p Ser10] Immunofluorescence](https://rocklandwebimagescdn.azureedge.net/webimages/600-401-I74-HistoneH3-pS10-Antibody-1-IF-4x3.jpg "Histone H3 [p Ser10] Immunofluorescence")
![Histone H3 [p Ser10] Western Blot](https://rocklandwebimagescdn.azureedge.net/webimages/600-401-I74-HistoneH3-pS10-Antibody-2-WB-2x5.jpg "Histone H3 [p Ser10] Western Blot")
![Histone H3 [p Ser10] Western Blot](https://rocklandwebimagescdn.azureedge.net/webimages/600-401-I74-HistoneH3-pS10-Antibody-3-WB-4x3.jpg "Histone H3 [p Ser10] Western Blot")
![Histone H3 [p Ser10] Dot Blot](https://rocklandwebimagescdn.azureedge.net/webimages/600-401-I74-HistoneH3-pS10-Antibody-4-DB-4x3.jpg "Histone H3 [p Ser10] Dot Blot")
Histone H3 phospho S10 Antibody
Rabbit Polyclonal
$50.00 to US & $70.00 to Canada for most products. Final costs are calculated at checkout.
Background
H3 pS10 is typically associated with activation of transcription of genes associated with histone H3. This modification is linked to the initiation of chromatin condensation in G(2). During mitosis, H3pS10 is required for proper chromosome segregation. Formation of the H3pS10 modification seems to be regulated in part by p53, which interacts with histone modifying complexes. In development of the retina, the presence of H3pS10 is linked to the abundance of eye defects. This developmental effect of H3pS10 seems to be related to Psf2 and GPR84. The human Timeless protein (Tim) regulates the global H3pS10 phosphorylation in G2/M phase. VASP concentrations peak during mitosis in HeLa cells at the same time as H3pS10, indicating that co-responsibility for transition of G2/M phases. AURKB promotes the phosphorylation of histone H3 at pS10. Anti-Histone H3 are ideal for researchers interested in Chromatin Modifiers, Chromatin Research, Histones and Modified Histones, and Epigenetics research.
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This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.