DUX4 Antibody
Mouse Monoclonal P2B1 IgG1
$50.00 to US & $70.00 to Canada for most products. Final costs are calculated at checkout.
Background
DUX4, or double homeobox4, is a human protein that is a transcriptional activator of paired-like homeodomain transcription factor 1. Clinically it is a facioscapulohumeral muscular dystrophy candidate gene that appears to have a toxic gain of function. In FSHD individuals, the expression of the full-length DUX4 transcript is not completely suppressed in skeletal muscle and possibly other differentiated tissues.
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