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Datasheet

GABA Transporter 1 (GAT1) Antibody

Rabbit Polyclonal

612-401-D56
100 µL
WB, IHC
Mouse, Rat
Rabbit
$475.00 /Per Item
Availability: Ships in approximately 14 days
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Background

Gamma-aminobutyric acid (GABA) Antibody detects GABA which is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl− channel associated with the GABAA receptor (GABAA-R) subtype. GABA plasma membrane transporters (GATs) influence synaptic neurotransmission by high-affinity uptake and release of GABA. To date, four distinct GABA transporters have been identified: GAT-1, GAT-2, GAT-3, and BGT-1. GAT-1, the most abundant of the transporters, is found predominantly in neurons, but also in some specialized glia. GAT-1 is thought to play a key role in epileptogenesis. Anti-GAT1 Antibody is ideal for investigators involved in Neuroscience.

Product Details

Anti-GABA Transporter 1 (GAT1) (RABBIT) Antibody - 612-401-D56
Sodium- and chloride-dependent GABA transporter 1, Solute carrier family 6 member 1, GAT-1, Slc6a1, Gabt1, Gat1
Rabbit
Polyclonal
IgG

Target Details

Slc6a1  - View All Slc6a1 Products
Mouse, Rat
Conjugated Peptide
Anti-GABA Transporter 1 Antibody was produced in rabbit by repeated immunizations with synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH.
Anti-GABA Transporter 1 antibody is directed against rat GABA Transporter 1. GABA Transporter 1 antibodies are affinity purified from monospecific antiserum by immunoaffinity purification. Reactivity is expected from the following species based on 100% sequence homology: mouse.

Application Details

IHC, WB
Anti-GAT1 (Rabbit) Antibody is tested for use in Western Blotting and IHC. Specific conditions for reactivity should be optimized by the end user. Expect a band at approximately 67 kDa in size corresponding to GABA Transporter 1 protein in the appropriate cell lysate or extract.

Formulation

Liquid
0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
0.1 mg/ml Bovine Serum Albumin (BSA) - IgG and Protease free, 50% (v/v) Glycerol

Shipping & Handling

Dry Ice
Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
Expiration date is one (1) year from date of receipt.

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This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.