Interleukin-1F5 is a recently discovered cytokine which was shown to specifically inhibit the activation of NF-kappaB induced by interleukin 1 family, member 6 (IL1F6) in humans. There is very little published regarding the bovine IL1F5 protein. In the human, this gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Expression of the gene appears to be restricted to various epithelial cell populations. Costelloe et al (2008) have identified SIGIRR [single immunoglobulin domain-containing IL1R-related protein] as a receptor for human IL1F5. Anti-IL-1F5 antibody antibody is ideal for investigators involved in Signal Transduction and Immunology research.
Interleukin 1 family, member 5 (Delta) . In humans it is also known as: IL1RP3, Il1hy1, Il-1h3, MGC29840, FIL1(DELTA), IL1F5, Il1f5, IL1L1, Fil1delta, IL1HY1, FIL1D, FIL1, or AI413231.
This protein-A purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a recombinant protein raised in yeast, corresponding to the 155 amino acids of the mature bovine IL-1F5 protein.