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Datasheet

CAND2 Antibody

Rabbit Polyclonal

100-401-A12
100 µL
WB, IP
Human, Mouse, Rat
Rabbit
$475.00 /Per Item
Availability: Ships next business day
Shipping info:

$50.00 to US & $70.00 to Canada for most products. Final costs are calculated at checkout.

Background

Anti-CAND2 antibody is ideal for western blotting, ELISA and IHC. CAND2 is also known as TIP120B, and TATA-binding protein-interacting protein 120B.  While both CAND1 (TIP120A) and CAND2 (TIP120B) are TATA-binding proteins and form complexes with various nuclear proteins involved in the control of eukaryotic gene transcription, CAND2 (TIP120B) is expressed specifically in muscle and heart tissue.  This is contrary to the ubiquitous expression of CAND1 (TIP120A). TIP120 homologs exist in various higher eukaryotes including D. melanogaster, C. elegans, and A. thaliana. TIP120B is 60% identical in amino acid sequence to TIP120A.

Product Details

Anti-CAND2 (C-terminal specific) (RABBIT) Antibody - 100-401-A12
rabbit anti-CAND2 Antibody, Cullin associated NEDD8 dissociated protein 2 antibody, p120 CAND2 antibody, TATA binding protein interacting protein 120B antibody, TBP interacting protein antibody, Tp120b antibody
Rabbit
Polyclonal
Antiserum

Target Details

CAND2  - View All CAND2 Products
Human, Mouse, Rat
Conjugated Peptide
This antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 1130-1143 of Human CAND2/TIP120B (C-terminal) coupled to KLH.
This product is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration. This product reacts with human, rat and mouse CAND2/TIP120B.  Cross reactivity does occur with human, rat and mouse CAND1/TIP120A.  Cross reactivity with CAND2 from other sources is not known.

Application Details

IP, WB
This antibody reacts with human, rat,  and mouse CAND2 tested by western blot and immunoprecipitation.  The antibody immunoprecipitates in vitro translated protein and protein from transfected cell lysates (using HeLa and NIH-3T3, and others).  Coimmunoprecipitation of related proteins has not been tested.  A 125.4 kDa band corresponding to human CAND2 is detected.  CAND2 is specifically expressed in muscle and heart tissue.  Researchers should determine optimal titers for other applications.

Formulation

Liquid (sterile filtered)
85 mg/mL by Refractometry
None
0.01% (w/v) Sodium Azide
None

Shipping & Handling

Dry Ice
Store CAND2 antibody at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
Expiration date is one (1) year from date of receipt.

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This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.